Application of spectral-focusing-CARS microscopy to pharmaceutical sample analysis
Application of spectral-focusing-CARS microscopy to pharmaceutical sample analysis
Blog Article
We implement spectral-focusing-CARS hyperspectroscopy to characterize pharmaceutical samples.The use of a dynamically-power-tuned supercontinuum seeding method combined with epi-detection of the CARS signals allows for broadband hyperspectroscopy and Wind Chimes rapid single vibrational frequency imaging with microsecond pixel dwell times.The broad hyperspectral Board Games New Sealed Childrens Games capabilities spanning about 3000 cm-1 of vibrational information allow for facile discrimination between ibuprofen, common polymorphs of acetaminophen, and starchy binders.Application of 3-D hyperspectral imaging on bare tablet forms reveals surface-bound processing of low-dose drugs such as cetirizine.